abstract |
The invention raktin mark A (macrolactin A), 7- O - malonyl mark raktin this (7- O -malonyl macrolactin A), 7- O - succinyl raktin mark this as (7- O -succinyl macrolactin A) The present invention relates to a composition having an angiogenic effect containing macrolactin compounds as an active ingredient. The macrolactin compounds provided by the present invention strongly inhibited neovascularization in in vivo experiments, and can be used as pharmaceutical compositions for preventing or treating diseases caused by angiogenesis. |