| abstract |
The present invention relates to a UV protective composition comprising a BLT2 inhibitor, and more particularly, by over-expression of cell membrane proteins BLT2, their ligands, and their synthetase by ultraviolet irradiation to generate reactive oxygen species and activate MAP kinase. Inhibiting the expression of the protein that induces apoptosis and inhibits the expression of the skin or hair effectively from the ultraviolet light by identifying it can be used in skin protection agents, skin inflammatory agents, sunscreen skin protection agents and the like.n n n n Keratinocytes, UVB, apoptosis, ROS, BLT2, Nox1, LTB4, 12 (S) -HETE |