abstract |
The present invention relates to an IL-17 receptor A (IL-17RA or IL-17R) antigen binding protein, eg, an antibody, a polynucleotide sequence encoding said antigen binding protein, and an IL-17 receptor by one or more IL-17 ligands. A composition and method for diagnosing and treating a disease mediated by A activation. The present invention relates to the identification of neutralizing determinants on IL-17 receptor A (IL-17RA or IL-17R) and antibodies binding thereto. Aspects of the present invention also include antibodies that compete with the IL-17RA neutralizing antibodies described herein for binding.n n n n IL-17 receptor A, IL-17RA, IL-17R, antigen binding proteins, antibodies, IL-17 ligands, IL-17RA neutralizing antibodies |