| abstract |
The present invention relates to blocking, inhibiting, decreasing, antagonizing or neutralizing the activity of the IL-22, IL-20, or polypeptide molecules of both IL-20 and IL-22. IL-20 and IL-22 are cytokines involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, and methods of antagonizing IL-22 or IL-20 and IL-22 using such antibodies and binding partners.n n n IL-22, IL-20, IL-22RA, inflammation, disease, treatment, antibody |