http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101232233-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 |
| filingDate | 2010-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101232233-B1 |
| titleOfInvention | Method for producing (S) -bepotastine |
| abstract | The present invention relates to a method for preparing (S) -bepotastine represented by the following formula (1), and more specifically, to a new intermediate (RS) -bepotastine- (S) -methylbenzylamide as an organic solvent. Optical separation under step to prepare (S) -bepotastine- (S) -methylbenzylamide (step 1); And (S) -bepotastine prepared by reacting (S) -bepotastine- (S) -methylbenzylamide obtained in step 1 under acidic conditions (step 2). )-Bepotastine. According to the present invention, (S) -bepotastine having a high production yield and an optical purity of at least 99.0% can be prepared by performing optical splitting using an intermediate not mentioned before: [Formula 1] . |
| priorityDate | 2010-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.