http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101229369-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9136549e91ac59221f028789b57cfb0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0cafdbce121d7662ac28d942576cd77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0213378e3f79cc37c62b21527991e5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea99c971b42cd4237cf6cfe5869b2f50 |
| publicationDate | 2013-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101229369-B1 |
| titleOfInvention | [E] N [2oxo1 [4oxo3,4-dihydrophthalazine1] 2 [2 [[4oxo4Hchromen-3day] methylene] hydrazinyl] ethyl] benzamide as an active ingredient Pharmaceutical composition for preventing and treating neurodegenerative diseases |
| abstract | The present invention provides (E) -N- (2-oxo-1- (4-oxo-3,4-dihydrophthalazin-1-yl) -2- (2-((4-oxo-4H-chrome) Men-3-yl) methylene) hydrazinyl) ethyl) benzamide ((E) -N- (2-oxo-1- (4-oxo-3,4-dihydrophthalazin-1-yl) -2- (2 A pharmaceutical composition for preventing and treating neurodegenerative diseases containing-((4-oxo-4H-chromen-3-yl) methylene) hydrazinyl) ethyl) benzamide) or a pharmaceutically acceptable salt thereof as an active ingredient. In particular, the compound according to the present invention specifically inhibits the degradation of Aβ by specifically inhibiting the S1 pocket of GCPII, thereby enhancing synaptic activity, and may play an important role in maintaining homeostasis of Aβ according to the progression of the disease. It can be usefully used as a pharmaceutical composition for the prevention and treatment of. |
| priorityDate | 2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 620.