http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101228106-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate | 2011-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101228106-B1 |
titleOfInvention | Nanocarriers with increased skin permeability, cell influx, and tumor transfer |
abstract | The present invention provides a biopolymer-modified nanocarrier in which chitosan is bonded to a water-soluble biocompatible polymer that is crosslinked through a photo-crosslinkable functional group at the end, wherein the chitosan-modified nanocarrier is subjected to temperature change. As a result, diameter changes and chitosan does not bind to bare nanocarriers, which increases skin permeability or cellular uptake and selective delivery to cancer tissues. The chitosan-modified nanocarriers of the present invention have improved skin permeability to a very surprising level compared to bare nanocarriers without chitosan, thus exhibiting very good efficacy as transdermal carriers. The chitosan-modified nanocarriers of the present invention have greatly improved cell influx into tumor cells and cancer cells, and thus can be very useful for imaging and photothermal treatment of tumor cells and cancer cells. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019156366-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102484332-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190096149-A |
priorityDate | 2010-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 784.