abstract |
The present invention provides a novel double-target antibody in which a water-soluble ligand is fused to the N-terminus of the heavy or light chain of an antibody, DNA encoding the double-target antibody, recombinant expression vector containing the DNA, and transfection with the recombinant expression vector. The present invention relates to a converted host cell and a method for producing a double target antibody by culturing the host cell and a pharmaceutical composition comprising the double target antibody.n n n n VEGFR-2, Tie-2, dual target antibody, neovascularization |