| abstract |
The present invention provides methods and compositions for treating ion imbalance. In particular, the present invention provides core-shell compositions and pharmaceutical compositions thereof. Disclosed herein are methods of using the core-shell composition for therapeutic and / or prophylactic effects. Examples of such methods include the treatment of phosphate imbalance, hypertension, chronic heart failure, end-stage renal disease, cirrhosis, chronic renal failure, fluid overload, or sodium overload. |