| abstract |
The present invention provides an 8-oxoadenine compound represented by the following formula (1) or a pharmaceutically acceptable salt thereof:n n n [In formula, ring A represents a 6-10 membered aromatic carbocyclic ring, etc., R represents a halogen atom, an alkyl group, etc., n represents the integer of 0-2, Z < 1> Represents an alkylene group, X 2 represents oxygen, sulfur, SO 2 , NR 5 , CO, CONR 5 , NR 5 CO and the like, Y 1 , Y 2 and Y 3 independently represent a single bond or an alkylene group, X 1 represents oxygen, sulfur, NR 4 (R 4 represents hydrogen or an alkyl group), or a single bond, and R 2 represents a (non) substituted alkyl group, and R 1 Represents hydrogen, a hydroxyl group, an alkoxy group, an alkoxycarbonyl group, a haloalkyl group, etc.].n n n It has an immunomodulatory effect such as interferon inducing activity and is useful as an antiviral agent, an antiallergic agent, or the like. |