| abstract |
The present invention provides a polynucleotide adjuvant composition and a method of using the same to generate an immune response. The present invention also provides immunogenic compositions comprising (eg in a vaccine) a polynucleotide adjuvant composition with an antigen. The adjuvant compositions of the present invention have particular physical properties (such as molecular weight, concentration, and pH) that address the need for safe adjuvant for eliciting an enhanced immune response. The present invention also includes methods of using such adjuvant compositions to elicit an immune response, particularly against antigenic compounds. n n Polynucleotide adjuvant compositions, immune responses, antigenic compounds, immunogenic compositions, molecular weight, molecular size, rabies vaccine. |