Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-16 |
filingDate |
2005-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2012-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101201464-B1 |
titleOfInvention |
Bispecific Binders for Modulating Biological Activity |
abstract |
Disclosed herein are methods for improving the biological and pharmaceutical properties of bispecific binding agents, which can be targeted by the high affinity binding domain to the first cell surface marker that does not cause significant biological effects. In addition, the low affinity binding domain that specifically binds to the second cell surface marker produces the desired biological effect. Also provided are compositions of these bispecific binders, uses for them, and kits comprising them. |
priorityDate |
2004-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |