http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101193464-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 |
| filingDate | 2005-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101193464-B1 |
| titleOfInvention | Adamantyl pyrrolidin-2-one derivative as a 11-beta hydroxysteroid dehydrogenase inhibitor |
| abstract | Compounds of formula (I), N-oxide forms, pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof:n n n n n n n n Wherein,n n n n is 1 or 2; M is a direct bond, or C 1 - 4 alkyl, C 1 - 3 alkyloxy -C 1 - 4 alkyl-, hydroxy -C 1 - 4 alkyl-, hydroxy, C 1 - 3 alkyloxy-phenyl, or -C 1 - 4 alkyl-represents an alkyl linker 3-a C 1 optionally substituted by one or two substituents selected from; R 1 and R 2 are each independently hydrogen; Halo; Cyano; Hydroxy; The optionally substituted by halo C 1 - 4 alkyl; Hydroxy, by one or, if possible, two or three substituents selected from halo and Ar 1 is optionally substituted C 1 - represents a-4 alkyloxy; R 3 is hydrogen, halo, C 1 - 4 alkyl, C 1 - 4 alkyloxy -, cyano, or represents a hydroxyl; R 4 is hydrogen; Halo; C 1 - 4 alkyl; Hydroxy; Cyano; Or hydroxy, and, if available, or to one selected from halo, or two to three substituents optionally substituted by a C 1 - represents a-4 alkyloxy; R 5 is hydrogen, C 1 - 4 alkyl or Ar 2 -C 1 - represents a 4-alkyl; R 6 is hydrogen, hydroxy, halo, C 1 - 4 alkyl or C 1 - 4 alkyl-oxy-represents; R 7 represents hydrogen or R 7 and R 5 together with the carbon atoms bonded thereto form a —C 2 -alkyl-linker; Ar 1 and Ar 2 represents a phenyl or naphthyl, each independently, wherein the phenyl and naphthyl are C 1 - may optionally be substituted by a 4-alkyl-4-alkyl, C 1 - 4 alkyl-oxy-phenyl, or -C 1 . |
| priorityDate | 2004-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.