http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101169373-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-51 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate | 2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101169373-B1 |
| titleOfInvention | Small Interference RNA Complex with Increased Intracellular Delivery Capability |
| abstract | The present invention relates to multisiRNA complexes and multifunctional nucleic acid structure complexes with increased intracellular delivery capacity. The siRNA complex and the multifunctional nucleic acid structure complex according to the present invention are a novel structure that can be easily chemically synthesized as compared to the shRNA system for suppressing the expression of a plurality of target genes, and at the same time, a plurality of genes can be simultaneously improved with improved efficiency. There is an advantage that can suppress expression. In addition, as well as having a high intracellular delivery capacity, it is possible to specifically inhibit the expression of target genes without causing a non-specific antiviral response, so as a siRNA-mediated therapeutic agent for treating cancer or viral infection, etc. useful. In addition, the multifunctional nucleic acid structure complex according to the present invention, by combining functional nucleic acid oligonucleotides such as miRNA, antagomiR, antisense oligonucleotide, aptamer and ribozyme in addition to siRNA to provide a variety of functions at the same time Can be. |
| priorityDate | 2009-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 231.