Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D203-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-14 |
filingDate |
2004-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101167335-B1 |
titleOfInvention |
Nitrophenyl mustard, nitrophenylaziridine alcohol and the corresponding phosphates, and their use as targeted cytotoxic agents |
abstract |
The present invention provides novel nitrophenyl mustards and nitrophenylaziridine alcohols, their corresponding phosphates, targeted cytotoxic agents, their use as bioreductive drugs in hypoxic tumors, and with nitroreducing enzymes. Relates to their use in cell excision, including gene-specific enzyme-prodrug therapy (GDEPT) and antibody-specific enzyme prodrug therapy (ADEPT). |
priorityDate |
2003-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |