| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 |
| filingDate |
2004-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2012-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101165278-B1 |
| titleOfInvention |
Optimized Expression of HPP 45 L1 in Yeast |
| abstract |
Synthetic DNA molecules are provided that encode the HPV45 L1 protein. In particular, the present invention provides polynucleotides encoding the HPV45 L1 protein, codon-optimized for high level expression in yeast cells. The synthetic molecules can be used to produce HPV45 virus-like particles (VLPs) and to produce vaccines and pharmaceutical compositions comprising HPV45 VLPs. The vaccine of the present invention provides effective immunoprevention against papillomavirus infection through neutralizing antibodies and cell mediated immunity.n n n n HPV45 L1 Protein, Virus-Like Particles, Codon-Optimization |
| priorityDate |
2003-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |