http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101161879-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-944 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2004-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101161879-B1 |
| titleOfInvention | Methods of Quantifying Botulinum Toxin |
| abstract | The present invention relates to a method for measuring the amount of presynaptic neuromuscular blocking substance (particularly botulinum toxin) contained in a sample. In one aspect, the method includes the following steps:n n n (Iii) measuring the minimum voltage V m necessary to induce contraction of muscle tissue, the muscle tissue being connected to an electrical stimulator via motor nerves, preferably immersed in oxidized physiological buffer containing glucose;n n n (Ii) adding a sample containing presynaptic neuromuscular blocking material;n n n (Iii) electrically stimulating muscle tissue at regular time intervals at a voltage at least equal to V m ;n n n (Iii) comparing the effect induced by the sample with the effect induced by the control, thereby measuring the amount of presynaptic neuromuscular blocking substance in the sample.n n n n Botulinum toxin, quantitative, presynaptic neuromuscular blocker, muscle tissue |
| priorityDate | 2003-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.