http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101161323-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10 |
| filingDate | 2009-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101161323-B1 |
| titleOfInvention | Method for producing dimers and multimers linked by bond crosslinking by increasing the formation of bond crosslinks in the repeating chain of the adhesive having a specificity to the monomer and the complex of the multimer |
| abstract | The present invention is to prepare an adhesive repeating chain in which an adhesive having an adhesive specificity to a monomer is repeatedly-connected, and a plurality of monomers are bonded to the repeating chain to form a repeating chain-multimeric monomer complex made of a repeating chain and various monomers. The present invention relates to a method for producing a multimer in which a plurality of monomers are linked by a bond crosslinking, by facilitating formation of a bond crosslinking between monomers in a composite. n More specifically, the present invention provides an adhesive protein repeat chain recombinant protein in which an adhesive protein having adhesion specificity to a protein monomer is repeatedly linked, and attaches a plurality of protein monomers to the repeat chain protein to the repeat chain and various monomers. The present invention relates to a method for producing a multimer in which a plurality of monomers are linked by a bond crosslinking by making a repeating chain-multimer complex made by the same and facilitating formation of a bond crosslinking between monomers in the complex. n More specifically, the present invention provides an adhesive protein repeat chain recombinant protein in which an adhesive protein having adhesion specificity to a protein monomer is repeatedly linked, and attaches a plurality of protein monomers to the repeat chain protein to the repeat chain and various monomers. The present invention relates to a method for producing a multimer in which a plurality of monomers are linked by disulfide bond crosslinking by making a repeating chain-multimer complex made by the same and facilitating formation of disulfide bond crosslinking between monomers in the complex. n More specifically, this domain III repeat chain protein is used as a binding matrix by using a recombinant repeating chain protein in which domain III (Fab adhesion domain) of protein G of Streptococcal is repeatedly-linked. By attaching a plurality of antibody protein monomers to the repeating chain and a plurality of antibody monomer complexes to facilitate the formation of disulfide bond crosslinks between the antibody monomers in the complex, a plurality of monomers are linked to the disulfide bond crosslinks and a large amount A method of producing a sieve. n The method of the present invention can be usefully used for mass production of disulfide bonded crosslinked dimers by improving the yield of disulfide bonded crosslinked dimers by up to 200 times compared to conventional refolding methods compared to the known refolding methods. . n n Monomers, dimers, multimers, repeating chains, recombinant proteins, repeating chain-multimeric complexes, binding crosslinking, crosslinking, disulfide bond crosslinking. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014193193-A1 |
| priorityDate | 2009-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.