http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101151004-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 |
filingDate | 2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101151004-B1 |
titleOfInvention | Attenuated Salmonella mutant strain transformed with an attachment factor of bovine pathogenic E. coli and vaccine composition for the prevention and treatment of bovine coliform bacterium and Salmonella bacterium |
abstract | The present invention is a Salmonella mutant strain transformed into attenuated Salmonella bacteria that have deleted the asd , lon and cpxR genes, including the adhesin gene of bovine pathogenic E. coli; And it provides a vaccine composition for the prevention and treatment of bovine pathogenic E. coli and Salmonella. In addition, the present invention is a method for producing the Salmonella mutant strain; And Salmonella mutant strain expressing the secretion of the adhesion factor prepared by the above method to prepare a live or dead bacterium vaccine, characterized in that the inoculation to cattle or jaws, vaccination method for the prevention and treatment of bovine pathogenic Escherichia coli and Salmonella bacterium to provide. As a result, E. coli-derived antigens are efficiently delivered to bovine mucosal lymphoid tissues to induce potent mucosal immunity, and vaccine production and mass vaccination are possible. There is one economic effect. Therefore, it can be used as a multivalent vaccine because it not only prevents infection by inducing an immune response against Salmonella bacteria, but also induces an immune response against an expressing external antigen.n n n n Small pathogenic Escherichia coli, salmonella, attenuated, vaccine, adhesion factor |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101371355-B1 |
priorityDate | 2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.