abstract |
The present invention provides a peptide effective for preventing cell damage having the amino acid sequence of SEQ ID NO: 1, and a pharmaceutical composition for preventing cell damage, comprising the peptide as an active ingredient. Peptides according to the present invention not only have a remarkably superior physiological activity in the protective activity of various cells compared to the conventional natural human erythropoietin, but also has a significantly simpler structure compared to the natural human erythropoietin, so that tissue-blood barrier (tissue-blood barrier) It is easy to pass through and the production cost is low. Therefore, the pharmaceutical composition comprising the peptide according to the present invention as an active ingredient is a stroke, mechanical damage or ischemic damage of the nervous system, myocardial infarction, diabetes mellitus, heart failure, peripheral vascular disorders, diabetic retinopathy, diabetic nephropathy, diabetic neurosis, It is effective for the prevention or treatment of neurodegenerative, acute and chronic renal dysfunction such as glaucoma, dementia, Parkinson's disease, Lou Gehrig's disease. |