http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101145381-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1307 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate | 2010-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101145381-B1 |
| titleOfInvention | A composition for inducing the differentiation of somatic cells into embryonic stem cell-like cells using oxysterol and WWP2 siRNA, and a method for producing embryonic stem cell-like cells using the same |
| abstract | A) Oxysterol; And b) a composition for inducing the differentiation of somatic cells including WWP2 siRNA into pseudo-cells, and a method for producing embryonic stem cell-like cells using the same. As described above, the present invention provides a method of inhibiting the expression of Oct4 by using WWP2 siRNA while inducing into cells such as neural stem cells by treating oxhterol (hydroxycholesterol), an Shh analogue which is an upper regulator of Bmi1 The present invention provides a method of inducing a new de-differentiation without the introduction of genes for the reverse differentiation by producing embryonic stem cell-like cells by inhibiting the expression of WWP2 and inhibiting the expression of Oct4, Like cells, embryonic stem cells have the ability to differentiate and can be used to treat various diseases and the like. |
| priorityDate | 2010-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.