http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101145376-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
filingDate | 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101145376-B1 |
titleOfInvention | A method for producing stem-like stem cell-like cells by reprogramming by the introduction of Bmi1 gene and stem cells prepared by the method |
abstract | The present invention provides a method for producing a Bmi1 protein comprising the steps of: i) introducing a nucleic acid molecule encoding Bmi1 (B cell-specific Moloney murine leukemia virus integration site 1) protein or Bmi1 protein into somatic cells; And ii) culturing the cells in a neural stem cell culture condition containing bFGF. The present invention also relates to a method for producing stem cell-like cells from somatic cells through reprogramming. According to the present invention, a method of inducing the differentiation by introducing a new factor in addition to the existing four genes (Oct4, Sox2, Klf4, and C-Myc / Oct4, Sox2, Nanog and Lin28) And regulate the conditions to provide an upper mesenchymal stem cell-like cell having a differentiation ability. |
priorityDate | 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.