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filingDate 2009-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101144237-B1
titleOfInvention Method of finding pharmacologically active substances of natural products by high resolution mass spectrometry and pharmacological activity test
abstract The present invention relates to a method for detecting a pharmacologically active component contained in a plurality of samples at a high speed by preparing a activity profile by examining pharmacological activity of a plurality of samples and analyzing the sample by a mass spectrometry And determining a molecular weight of the pharmacologically active substance by comparing and analyzing the activity profile and the mass profile of the pharmacologically active substance. The present invention can quickly find a pharmacologically active substance by determining a molecular formula of a large number of constituent compounds contained in a sample of a natural substance extract using a high-resolution mass spectrometer from a high-resolution mass spectrum and comparing it with activity test data. Information on the intensity of activity by pharmacologically active substance activity data enables efficient use of natural products. n n Natural extract, fractionation, activity test, high resolution mass spectrometer, molecular formula, pharmacologically active substance
priorityDate 2009-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 37.