| abstract |
Pantoprazole sodium multiparticulate is disclosed that does not adhere to the nasogastric and gastrotypic tubes. The pantoprazole composite microparticles may comprise a subcoat consisting of a spherical core, hydroxypropyl methylcellulose (hypromellose) and water, including pantoprazole or an enantiomer thereof or a salt thereof, a surfactant and a disintegrant, An enteric coating on the lower coating, and a final sealing coating consisting of hydroxypropyl methylcellulose (hypromellose) and water on the enteric coating. |