http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101130754-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-66 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-01 |
filingDate | 2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101130754-B1 |
titleOfInvention | Pharmaceutical composition with improved solubility of poorly soluble tricyclic derivative compounds |
abstract | The present invention relates to a pharmaceutical composition with improved solubility of tricyclic derivative compounds including nanoparticles consisting of phospholipids, cholesterol, ionic lipids and tricyclic derivative compounds. It is possible to solubilize adult tricyclic derivative compounds in high concentrations without the use of solubility aids harmful to the human body, to maintain improved solubility even when water is added for later use as injections and to show stability even for long-term storage. Therefore, the lipid nanoparticles of the present invention can be usefully used for the preparation of pharmaceutical preparations having an insoluble tricyclic derivative compound as an active ingredient. |
priorityDate | 2010-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.