http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101129456-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-32 |
filingDate | 2005-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101129456-B1 |
titleOfInvention | Solid preparations with improved solubility and stability and methods for their preparation |
abstract | The present invention relates to a solid preparation having improved solubility while maintaining the stability of the preparation by adding a formulation to a poorly water-soluble chemical substance as a medicinal active ingredient. Specifically, it is a solid preparation comprising a poorly water-soluble chemical substance, a water-soluble polymer substance and an inorganic porous substance as a medicinal active ingredient, (1) the poorly water-soluble chemical substance forms a solid dispersion together with the water-soluble polymer substance, (2 (3) The water-soluble polymer material forming the solid dispersion is in the form of microflakes, and (3) the water-soluble polymer material in the form of the microflakes is adsorbed and / or adhered to the surface of the inorganic porous material. It is a solid formulation with improved solubility. These solid preparations can be prepared by stirring and mixing a solution obtained by dissolving a poorly water-soluble chemical substance and a water-soluble high molecular substance as a pharmaceutically active ingredient in an organic solvent, followed by granulation and drying. |
priorityDate | 2004-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 379.