| abstract |
The present invention provides substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds described selectively inhibit one or two Akt isoforms. The present invention also provides compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compounds to a patient in need thereof.n n n Substituted Naphthyridine Compounds, Inhibition of Akt Activity, Akt Inhibitors, Treatment of Cancer |