http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101099705-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101099705-B1 |
| titleOfInvention | Inhibitor of cancer cell growth and anti-cancer drug sensitivity by regulating CAN1 protein |
| abstract | The present invention relates to cancer cell growth inhibition and anticancer agent sensitivity enhancer through protein regulation associated with colorectal cancer, and more particularly, to an anticancer agent sensitivity enhancer containing an inhibitor of the expression or action of CANu1 protein having the amino acid sequence of SEQ ID NO. It is about.n n n According to the present invention, after inhibiting the expression of CANu1 protein in cells subjected to DNA damage, whether CANu1 protein expression, which is a protein associated with colorectal cancer, is effective in cancer cell apoptosis when the anticancer agent is administered, doxorubicin, vinblastine and When examining the sensitivity of cancer cells to anticancer drugs such as Taxol, it was confirmed that the cancer cells are sensitive to the anticancer drugs and effectively induce apoptosis. Therefore, by using the inhibitor of the expression or action of the CANu1 protein, it is possible to expect an effective cancer treatment effect by using a low concentration of anticancer agents. |
| priorityDate | 2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 299.