http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101097850-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2511-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-76 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate | 2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101097850-B1 |
| titleOfInvention | Zeldanamycin biosynthesis regulatory gene mutants and method for producing geldanamycin |
| abstract | The present invention relates to a geldanamycin biosynthesis regulatory gene mutant strain and a method for producing geldanamycin using the same, and more particularly, to streptomyces hygroscopy for producing geldanamycin, a metabolite having thermal shock protein inhibitory activity. kusu subspecies Dua Mai Shetty kusu (Streptomyces hygroscopicus subsp. duamyceticus) in strains geldanamycin was inactive the gene orf10 or gel19 involved in the production of the gene involved in the biosynthesis control strain, and culturing the strain in which inactive the orf10 gene The present invention relates to a method for mass production of geldanamycin. The geldanamycin exhibits an Hsp90 inhibitory effect and may be usefully used as an antibiotic, an antifungal agent, an antiviral agent, an immunosuppressive agent, an anti-inflammatory agent or an anticancer agent.n n n n Zeldanamycin, streptomyces, regulatory genes, strain improvement. |
| priorityDate | 2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.