| abstract |
[PROBLEMS] In the transdermal absorption preparation of natural sex hormones, the stability and skin permeability of the natural sex hormones are improved to improve the effects and maintenance of the systemic action. [Resolution] Two or more oils selected from polyoxyethylene oleyl ether having an added mole number of ethylene oxide of 20 with natural sex hormone, adipic acid diisopropyl, cetyl alcohol, benzyl alcohol and propylene glycol dicapric acid And polyhydric alcohol and ethanol are blended. |