http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101082348-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2035-00158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2035-00346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L9-527 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2009-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101082348-B1 |
| titleOfInvention | Bead-Based Microchip with Temperature Control |
| abstract | The present invention relates to a bead-based microchip having a temperature control function, and more particularly, reaction by using a microbead having a ligand fixed on a surface thereof and a microchip having a heater for heating the reaction chamber in which the microbead is accommodated. Simultaneous denaturation and elution of the ligand and target protein bound to the surface of the microbeads by heating the chamber allows integration of the pre-process outside the conventional microchip into the chip, thereby detecting target protein. The present invention relates to a bead-based microchip equipped with a temperature control function that can reduce the chemical reaction time and simplify the test process to facilitate the diagnosis of disease in the antigen-antibody test.n n n The bead-based microchip having a temperature control function of the present invention includes: a body part having a first reaction chamber and a second reaction chamber structurally isolated to block heat transfer therebetween; Target protein fixation beads filled in the first reaction chamber and proteolytic beads filled in the second reaction chamber; A first heater part attached to and formed on a lower surface of the body portion on the side of the first reaction chamber and a second heater part attached to and formed on a lower surface of the body portion on the second reaction chamber side; A cover part attached to an upper surface of the body part and having a plurality of through holes formed as an entrance through which a sample moves in and out; A flow path part provided on an upper surface of the cover part and having a micro channel formed therein and connected to some of the plurality of through holes; And a flow control unit coupled to an upper surface of the flow path unit to control a flow of the fluid using a pneumatic valve, and coupled to the protein fixing bead surface by heating the first reaction chamber through the first heater unit. The denaturation and elution of the target protein is simultaneously performed, while the second reaction chamber is heated through the second heater to increase the activity of the proteolytic beads.n n n n Lab-on-a-chip, aptamers, microbeads, temperature, ligand, BAC, ELISA, MEMS |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9476038-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013118990-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101915675-B1 |
| priorityDate | 2009-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.