| abstract |
The present invention provides a method of modulating the activity of the hedgehog signaling pathway. In particular, the present invention encompasses abnormal growth conditions resulting from phenotypes such as Ptc function-loss, hedgehog function-acquisition, smoothing function-acquisition, or Gli function-acquisition, comprising contacting a cell with a sufficient amount of a compound of formula (I). It provides a way to suppress.n n n <Formula I>n n n n n n n n Hedgehog Signaling Path, Ptc Function-Loss, Hedgehog Function-Acquisition, Smoothing Function-Acquisition, Gli Function-Acquisition, Abnormal Growth |