abstract |
Disclosed are pharmaceutical compositions containing organic compounds of formula (I) or salts thereof that function as modulators for SDF-1 or I-TAC chemokines. The compounds and compositions are effective for inhibiting cancer, particularly cancer proliferation, growth and metastasis. Also disclosed are methods of interfering SDF-1 and / or I-TAC chemokine binding to the CCXCKR2 receptor and treating cancer using the compounds and pharmaceutical compositions of the invention.n n n n Formula I |