Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43504 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2010-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2011-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101046934-B1 |
titleOfInvention |
New Omega-Conotoxin |
abstract |
The present invention provides the ω-conotoxin so that the amino acid residues 11 and / or 12 are positioned in the secondary loop between cysteine residues 2 and 3 of the ω-conotoxin peptide represented by the following general formula I, respectively, so that Ile and Ala are located: A method of increasing the binding reversibility of an ω-conotoxin peptide to an N-type calcium channel comprising the step of preparing a peptide. The present invention also relates to novel ω-conotoxin peptides and pharmaceutical compositions having excellent properties with blocking activity and specificity for N-type calcium channels and significantly increased binding reversibility for N-type calcium channels. |
priorityDate |
2006-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |