abstract |
The present invention provides methods and reactants that are available for controlling proliferation or differentiation in cells or tissues, which method comprises contacting a hedgehog anti-inflammatory agent, for example the compound shown in FIGS. 32 and 33, with a cell. In certain embodiments, such methods and reactants can be used to inhibit / inhibit abnormal or unwanted growth states, for example by antagonizing normal ptc pathways or promoting smoothened or hedgehog activity. |