http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101037052-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D253-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
filingDate | 2009-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101037052-B1 |
titleOfInvention | 5-chloro-N-(((5S) -2-oxo-3- (4- (5,6-dihydro-1,2,4-triazine-1 (4H) -yl) phenyl) -1, Method for preparing 3-oxazolidin-5-yl) methyl) thiophene-2-carboxamide derivative and its intermediate |
abstract | The present invention relates to a compound of formula 1, 5-chloro-N-({(5S) -2-oxo-3- [4- (5,6-dihydro-4H- [1,], which is useful as an inhibitor of coagulation factor Xa. 2,4] triazin-1-yl) phenyl] -1,3-oxazolidin-5-yl} methyl) thiophene-2-carboxamide derivatives and intermediates thereof. 1-fluoro-4-nitrobenzene is used.n n n [Formula 1]n n n n n n n n [R 'is as defined in the detailed description of the invention.]n n n According to the preparation method of the present invention, 5-chloro-N-({(5S) -2-oxo-3- [4- (5), which is a compound of formula 1, which is useful as an inhibitor of blood coagulation factor Xa in a simpler manner than the conventional method. , 6-dihydro-4H- [1,2,4] triazin-1-yl) phenyl] -1,3-oxazolidin-5-yl} methyl) thiophene-2-carboxamide derivative with high purity And high yields.n n n Cyclic amidrazone, oxazolidinones, factor Xa inhibitors, anticoagulants |
priorityDate | 2009-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.