http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101026816-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate | 2003-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101026816-B1 |
| titleOfInvention | Error Reduction Method in Nucleic Acid Populations |
| abstract | The present invention relates to a method for the direct synthesis of double stranded DNA molecules of various sizes having any desired sequence. The DNA molecules to be synthesized are logically broken down into smaller overlapping DNA fragments. A maskless microarray synthesizer is used to prepare a DNA microarray on a substrate, wherein each component or each feature of the array is positioned with the DNA of one of the overlapping DNA fragments. The complement of each fragment is also prepared in a microarray. The DNA fragments are separated from the substrate and maintained under conditions that promote hybridization of DNA, where the fragments hybridize to form double strands. The double strand is then separated using a DNA binder that binds to the improperly formed DNA helix to remove the error from the DNA molecule set. The fragments can then be hybridized with each other to assemble a larger target DNA sequence. |
| priorityDate | 2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.