http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101019506-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-695 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-35 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2008-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101019506-B1 |
| titleOfInvention | Adrenal function evaluation index using cortisol and dehydroisoandrosterone concentration in saliva and adrenal function evaluation method using the index |
| abstract | The present invention relates to an indicator capable of quickly and objectively determining an adrenal state of an individual and a method for measuring adrenal state using the indicator. In detail, the indicator of the present invention includes the following two-dimensional map; A cortisol distribution function that is a sum of a first Gaussian function and a second Gaussian function; And a dehydroisoandrosterone distribution function which is a sum of a third Gaussian function and a fourth Gaussian function, wherein the x-axis of the two-dimensional map is a concentration of cortisol and the y-axis of the two-dimensional map is dehydro. It is the concentration of isoandrosterone (DHEA; dehydroepiandrosterone) and the ratio of cortisol concentration and dehydroisoandrosterone concentration is the value, and the cortisol distribution function is a concentration distribution of cortisol measured from saliva of the normal group without disease, respectively. The sum of a first Gaussian function and a second Gaussian function obtained by fitting to two Gaussian distributions having a weight of 0, wherein the dehydroisoandrosterone distribution function is a concentration distribution of dehydroisoandrosterone measured from saliva of the normal group. Is a third Gaussian function and a fourth Gaussian obtained by fitting the two Gaussian distributions with respective weights. A summation of the functions, wherein the region composed of the x-axis and the y-axis of the two-dimensional map is the intersection of the first Gaussian function and the second Gaussian function, a specific percentile of the first or second Gaussian function, The third Gaussian function and the fourth Gaussian function may be divided into regions by a specific percentile of the third or fourth Gaussian function, or a combination thereof.n n n The indicators of the present invention can provide a quick and objective criterion in the assessment of the health status of patients with a variety of clinical and non-clinical studies and adrenal related diseases, and are useful indicators for determining adrenal status associated with stress. Can be used asn n n n Saliva, cortisol, dehydroisoandrosterone, adrenal gland, indicator |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101447091-B1 |
| priorityDate | 2008-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.