http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101008001-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D10B2401-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D06M10-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D06M15-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0092 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B1-00 |
| filingDate | 2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101008001-B1 |
| titleOfInvention | Biodegradable nanofibers with improved drug delivery sustained release by fluorine treatment and preparation method thereof |
| abstract | The present invention relates to a biodegradable nanofiber with improved drug delivery sustained release and a method for producing the same, the method for producing a biodegradable nanofiber with enhanced drug delivery sustained release according to the present invention, (1) a polymer precursor, a water-soluble drug And mixing the solvent; (2) electrospinning the mixture obtained in step (1) to obtain nanofibers; (3) crosslinking the nanofibers by radiation treatment to the nanofibers obtained through the process of 'step (2)'; And (4) modifying the surface of the crosslinked nanofibers by fluorination of the crosslinked nanofibers obtained through the process of 'step (3)'.n n n According to the present invention, the hydrophobic functional group is introduced to the surface of the nanofiber formed by electrospinning and radiation treatment by fluorine treatment, thereby suppressing the decomposition rate of the biodegradable polymer. Therefore, the release rate of the drug contained in the nanofibers is suppressed, thereby controlling the release rate of the drug.n n n n Drug delivery, sustained release, fluorine, fluorine treatment, nanofiber, electrospinning |
| priorityDate | 2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.