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filingDate 2010-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c205078d1348d0baf1e8b12ff25de1ab
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publicationDate 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101004753-B1
titleOfInvention Transgenic Mice Expressing Luciferase Under the Control of Human IL-4 Promoter and Method for Making the Same
abstract The present invention relates to a transgenic mouse expressing luciferase under the control of a human interleukin-4 (IL-4) promoter and a method for preparing the same, and more particularly, to the human IL-4 promoter of SEQ ID NO: 1, Transformed mice produced by microinjecting a manufactured fusion gene linked to luciferase and CNS-1 (Conserved Non-coding Sequence) gene of SEQ ID NO: 3 into a fertilized egg of a mouse and transplanting the fertilized egg into a fallopian tube of a surrogate mother It relates to a manufacturing method. These transgenic mice have a human IL-4 promoter inserted to respond to external allergens and are very useful for effectively detecting allergens, which are allergens in the environment, by linking luciferase genes to measure response. Can be used.
priorityDate 2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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