http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101003331-B1

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filingDate 2010-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2010-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7daf684855144f7b6a6bcf2d0669e7f1
publicationDate 2010-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101003331-B1
titleOfInvention Skin filler composition
abstract The present invention is to solve the problems of the conventional skin fillers as described above, even if the cross-linked dextran having a molecular weight of 30,000 or more and 100,000 or less as the main component alone to maintain the rapid expansion and soft touch of the skin filler application area Unlike conventional dermal fillers containing collagen or hyaluronic acid as main ingredients, it does not contain collagen or hyaluronic acid, so it does not require pretreatment such as allergic reaction test before the procedure, and it is inexpensive. It is not suitable for use in surgery such as penis enlargement that requires injection of large amount of dermal filler of 20cc or more because it is not easily disintegrated and absorbed in the body and can maintain the volumetric effect by the procedure for a longer period of time. Dextran crosslinked with methylmethacrylate (PMMA) Unlike conventional skin fillers, which do not contain powder, they do not contain polymethylmethacrylate (PMMA), which eliminates the vague fear of the side effects that these components do not permanently decompose and remain in vivo. In addition, the manufacturing process is simpler, and the effect is easier to apply, and the new skin filler composition which can be used not only on the skin of the penis but also on the skin of a wide range of other parts of the human body, including the face, due to the soft touch when injected under the skin; It relates to a manufacturing method. In order to achieve the above object, the present invention relates to a composition of a new dermal filler, which is injected into the body through injection to give an arbitrary form quickly and maintains a soft touch, and more particularly, a crosslinked dex with a molecular weight of 30,000 or more and 100,000 or less. Provided is a dermal filler composition comprising tran, an aqueous sodium chloride solution and a viscosity modifier (excluding polymethylmethacrylate (PMMA)). In another aspect, the present invention is polymethyl peroxide solution containing 0.3 ~ 0.4g of cytotoxic removal crosslinked dextran 0.3 ~ 0.4g, pH 6 ~ pH 8 isotonic solution of 10 ~ 30,000 molecular weight per 10ml of the skin filler composition, containing a viscosity modifier 0.02 ~ 0.06g Except for including methacrylate (PMMA)] is provided a dermal filler composition. In another aspect, the present invention is the step of adding a physiological saline (0.9% aqueous sodium chloride solution) to 0.3 ~ 0.4g cross-linked dextran molecular weight of 30,000 or more 100,000 or less so that the solution of the dextran outer space is an isotonic solution; Adjusting the pH of the aqueous sodium chloride solution adjusted to the isotonic solution to pH6∼pH8; It provides a method for preparing a skin filler composition comprising the step of adding a viscosity modifier.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022004951-A1
priorityDate 2010-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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