| abstract |
The present invention relates to a collagen membrane produced herein from amnion as defined herein as collagen biofabric. The collagen biostructures of the present invention have a structural form of natural non-treated amnion, ie a natural tertiary or quaternary structure. The present invention provides a method of decellularizing amnion to produce collagen biostructures from placental membranes, preferably human placental membranes with chorion and amnion. In a preferred embodiment the amnion is completely decellularized. The collagen biostructures of the present invention have a variety of uses in the medical and surgical fields, including, for example, blood vessel regeneration, blood vessel manufacture and replacement, tendon and ligament replacement, wound-dressing, surgical transplantation, ophthalmic use, sutures and others. Have The benefits of this biostructure are due in part to biomechanical strength, flexibility, sutures and low antigenicity, especially when derived from the human placenta. |