| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_559ec3960c545c6b9f01db728ad39dba |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-08 |
| filingDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91ba4a5fea09616fd38512f402c6109
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ada2b9fa813c95bba71d2eea48ba263c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9d043ca866c3efa9569c868d15a47c1 |
| publicationDate |
2010-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-100971371-B1 |
| titleOfInvention |
Method for preparing barleyconazole using a novel intermediate |
| abstract |
The present invention relates to a method for preparing boriconazole of formula (1), and more particularly, to lipomaski coupling reaction of a ketone compound of formula (4) with a pyrimidine derivative of formula (5) to obtain a formula (3), and substituted halo and jade The sulphonyl is reacted with hydrogen or a hydrogen donor under a palladium catalyst to prepare racemate voriconazole of formula (2), which is then optically partitioned through a suitable optically active acid to yield high yield of voriconazole of formula (1) having high optical purity. And to a method of manufacturing economically. [Formula 1] |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101709543-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160069892-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101435741-B1 |
| priorityDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |