http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100970579-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-03074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100970579-B1 |
| titleOfInvention | Cytotoxic pyridoxal-5'-phosphate dephosphatase fusion protein |
| abstract | The present invention provides a pyridoxal-5'-phosphate dephosphorase which can be easily introduced into a cell by preparing a pyridoxal-5'-phosphate dephosphatase fusion protein in which a pyridoxal-5'-phosphate dephosphatase and a protein transport domain are covalently bound. As the kinase fusion protein, more specifically, the protein transport domain of the present invention is composed of 15 to 30 amino acids, hydrophilic domain (hydrophobic domain) comprising five or more tryptophan, hydrophilic domain including a large number of lysine ( A protein transport domain consisting of a hydrophilic domain and a spacer separating the two domains is fused to at least one terminus of pyridoxal-5'-phosphate dephosphatase, which is smoother in PC12 neurons compared to the control. Penetrates dependently and time-dependently, lasts more than 36 hours in cells and concentrates of intracellular pyridoxal-5'-phosphate The exhibited significantly lowering effects.n n n n Human Brain Pyridoxal-5'-Phosphate Dephosphatase (PLPP), PEP-1 Peptide, Protein Transduction, Protein Therapy, Pyridoxal-5'-Phosphate (PLP) |
| priorityDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 502.