http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100968838-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate | 2008-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100968838-B1 |
| titleOfInvention | A composition for drug delivery comprising the repeat region fragment of the EVF-like domain of Stabilin-2 as an active ingredient and use thereof |
| abstract | The present invention relates to a polypeptide comprising a repeat fragment of the EGF-like domain of Stabilin-2, a composition for detecting phosphatidylserine comprising the same, and more particularly, the use of stabilin-2 This is achieved by the fact that a polypeptide that is sequentially linked to a second atypical EGF-like domain and at least three EGF-like domains in an EGF-like domain repeat protein is specifically bound to phosphatidylserine. A polypeptide, a composition for detecting phosphatidylserine comprising the polypeptide, and a use thereof. The second atypical EGF-like domain and three or more EGF-like domains are sequentially linked in an EGF-like domain repeat protein (EGFrp) of stabilin-2 of the present invention. The polypeptide may specifically bind to phosphatidylserine on the cell surface. Therefore, the present invention can be used in various ways, such as drug delivery to cells expressing phosphatidylserine on the cell surface, prevention, treatment or imaging of tumor diseases through delivery of drugs or markers to tumor cells.n n n n Stabilin-2, EGFrp, Phosphatidylserine, Killing Cells, Tumor Disease |
| priorityDate | 2008-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 794.