http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100932997-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D323-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D323-04 |
| filingDate | 2002-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100932997-B1 |
| titleOfInvention | Novel substituted 1,2,4-trioxanes, useful as antimalarial agents, and a process for the preparation their of |
| abstract | The present invention relates to a new series of antimalarial 1,2,4-trioxane analogues of the general formula 7, and to the preparation thereof:n n n n n n n n Wheren n n R represents a cycloalkyl group selected from the group consisting of cyclopentyl, cyclohexyl, cycloheptyl and cyclooctyl, or an aryl group selected from the group consisting of phenyl, 4-bromophenyl and 4-chlorophenyl,n n n R 1 and R 2 are an alkyl group selected from the group consisting of hydrogen atom, methyl, ethyl, propyl and decyl, cyclopentane, cyclohexane, substituted cyclohexane, cycloheptane, bicyclo (2.2.1) heptane, adamantane Aryl selected from phenyl or part of a cyclic system such asn n n Some of these new compounds show promising antimalarial activity against multiple drug resistant malaria in mice.n n n Antimalarial activity, trioxane, drug resistance, endemic, treatment |
| priorityDate | 2002-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 245.