abstract |
The present invention is a dithiazole compound of formula (I) or a salt thereof, which has excellent activity inhibitory action against matrix metalloproteases (MMPs) and is useful for pharmaceutical compositions, cosmetic compositions, and external skin preparations.n n n Formula In n n n n n n n [R 1 is hydrogen atom, alkyl or the like; R 2 is hydrogen atom, hydroxy, alkyl, aryl, arylalkoxy, arylalkyl and the like; R 3 is a group of any one of Formulas II to IV:n n n Formula IIn n n n n n n n Formula IIIn n n n n n n n (IV)n n n n n n n n .] |