| abstract |
The present invention contains a compound of formula (I) wherein A, R 1 , R 2 , R 3 , R 4 and R 5 are each as described herein, or a pharmaceutically acceptable salt thereof, and the compound And symptoms mediated by 5-HT 4 agonistic activity of the compound, such as gastroesophageal reflux disease, gastrointestinal disease, gastric dyskinesia, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation In the treatment of diseases such as dyspepsia, esophagitis, gastroesophageal disease, nausea, central nervous system disease, Alzheimer's disease, cognitive impairment, vomiting, migraine, neurological disease, pain, cardiovascular disorders, heart failure, deep vein, diabetes and apnea syndrome Relates to the use of:n n n Formula I |