abstract |
Hydrazono-malonitrile derivatives of formula I act as phosphodiesterase IV inhibitors and act as osteoporosis, tumors, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes, inflammatory reactions, allergies, asthma, autoimmune diseases Can be used to treat myocardial diseases and AIDS:n n n [Formula I]n n n n n n n n Wherein R 1 , R 2 , R 3 , R 3 ′ and R 4 have the meaning set forth in claim 1. |