http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100892864-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-3221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-32213 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F25-43141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-242 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-24 |
filingDate | 2002-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100892864-B1 |
titleOfInvention | Process for the preparation of amino-protecting derivatives of 4-aminomethylene-pyrrolidin-3-one and / or 4-aminomethylene-pyrrolidine-3-alkoxyimino derivatives and / or gemifloxacin or salts thereof |
abstract | The present invention provides a process for the preparation of a compound of formula (I) consisting of comprising the protection of a compound of formula (II) in solution phase continuous mode of operation: wherein P 1 and P 2 may be the same or different and And amino protecting groups. This offers advantages over batch mode of operation. The process is usually performed in a reaction apparatus configured for use in a continuous mode, such as, for example, comprising one or more static mixers or an extrusion flow reactor. Preferably, the extrusion flow reactor is jacketed with internal mixing elements installed therein which continuously divide and remix the reaction streams to promote material and heat transfer, thereby allowing a uniform extrusion flow profile with vortex fluid flow to be obtained. It consists of including a tubular reactor. The present invention also provides a process for the preparation of the antimicrobial compound zemifloxacin or pharmacologically acceptable salts and / or hydrates thereof, which comprises converting the compound of formula (I). The present invention also provides a process for preparing the compound of formula (VIIa). n (Ⅰ) (Ⅱ) (Ⅷa) |
priorityDate | 2001-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.